COMPARATIVE PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF COFFEA ARABICA LEAF EXTRACTS

S. Uzoma

Abstract


Coffea Arabica leaves was analysed for its phytochemical constituents and its antimicrobial activity. Extracts of n-hexane, ethylacetate, acetone, chloroform and methanol respectively were used in the order of increasing polarity. The phytochemical screening revealed the presence of tannins, saponins, flavonoids, terpenoids, alkaloids, simple sugar (carbohydrates). With the exception of glycosides, all the phytochemicals tested were detected in the sample at varying degrees. Chloroform and methanol extracts of the leaves of coffee arabica were studied for their antibacterial efficacy and antifungal activity. The antimicrobial activities results obtained revealed that the extracts of leaves showed antibacterial activity against Escherichia coli and Staphylococcus aureus except n-hexane. The presence of bioactive compounds and result of antimicrobial activities are an indication that Coffea arabica leaves has medicinal activity.

Keywords: Coffea arabica, phytochemicals, minimum inhibitory concentration (MIC)


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